危地马拉圣卡洛斯大学（Universidad de San Carlos de Guatemala，简称USAC）创建于1676年，是危地马拉唯一的国立大学，也是美洲最古老的高等学府之一。作为该国规模最大的公立高等教育机构，USAC在学术研究和社会服务领域具有深远影响力，培养了包括医学、法学、工程学等多个领域的杰出人才。

Founded in 1676, the Universidad de San Carlos de Guatemala (USAC) is the only national university in Guatemala and one of the oldest higher education institutions in the Americas. As the largest public higher education institution in the country, USAC has far-reaching influence in academic research and social services, nurturing outstanding talents in various fields including medicine, law, and engineering.

该校设有10个院系和4个专业学院，涵盖农艺学、建筑学、法律与社会科学、医学、工程学等广泛学科。其教学语言以西班牙语为主，部分研究生课程提供英语授课选项。USAC在中美洲地区享有较高声誉，2025年QS世界大学排名位列1201-1400区间，拉丁美洲地区排名第161位。

The university comprises 10 faculties and 4 specialized schools, covering diverse disciplines such as agronomy, architecture, law and social sciences, medicine, and engineering. Spanish is the primary language of instruction, with select graduate programs offering English-taught options. USAC holds a strong regional reputation, ranking in the 1201-1400 range in the 2025 QS World University Rankings and 161st in Latin America.