巴黎科学艺术人文大学（法文：Université PSL；英文：Paris Sciences & Lettres – PSL University，简称PSL）坐落于法国巴黎，是一所享誉世界的研究型大学。该校组建于2010年，汇集了24所巴黎历史悠久的高等院校及研究机构，在工学、文学、理学、经济学和医学等领域具有崇高学术地位。PSL是法国“卓越大学计划”成员，培养了3位法国总统、1位塞内加尔总统，其校友、教授及研究人员中诞生了33位诺贝尔奖得主、14位菲尔兹奖得主，在2025年QS世界大学排名中位列第24位。

Paris Sciences & Lettres – PSL University (French: Université PSL), located in Paris, France, is a world-renowned research university. Established in 2010, it brings together 24 historic Parisian institutions of higher education and research, holding eminent academic status in engineering, literature, science, economics, and medicine. As a member of France's "Initiatives d'Excellence" program, PSL has educated 3 French presidents and 1 Senegalese president. Its alumni, professors, and researchers include 33 Nobel laureates and 14 Fields Medalists, ranking 24th in the 2025 QS World University Rankings.

PSL的学科设置融合科学、工程、艺术与人文，涵盖自然科学与工程、人文与社会科学、艺术与设计等领域，并强调跨学科研究。旗下成员机构包括以理科见长的巴黎高等师范学院、商科突出的巴黎第九大学、工科领先的巴黎高等矿业学校及医科权威居里研究所等，整合了法国国家科学研究中心（CNRS）等机构的实验室资源，致力于打破学科壁垒，推动创新与交叉合作。

PSL's academic offerings integrate science, engineering, arts, and humanities, covering natural sciences & engineering, social sciences & humanities, arts & design, with a strong emphasis on interdisciplinary research. Its member institutions include the École Normale Supérieure (excellence in science), Université Paris Dauphine (strength in business), Mines ParisTech (leading in engineering), and Institut Curie (authority in medicine). It integrates laboratory resources from institutions like the French National Centre for Scientific Research (CNRS), aiming to break disciplinary barriers and foster innovation and interdisciplinary collaboration.